Sabino-1

News Item

April, 2014
New test available for dogs. Please see Canine Genetic Tests

News Item

March, 2014
Animal Genetics purchases an additional genetic analyzer (ABI3130xl) to handle increased demand and improve service.

News Item

February, 2013
In a blind study published in The Journal of Avian Medicine and Surgery conducted by Dr. Geoff Olsen and Dr. Brian Speer, Animal Genetics / Avian Biotech was the only laboratory to get a perfect score on all positive and negative test results. One lab reported 8 out of ten negative samples as positive.

News Item

January, 2013
Animal Genetics publishes 3rd paper on Avian Borna Virus in Avian Diseases. Please contact us for a copy.

Sabino-1

Description:

In the heterozygous state, the Sabino coat pattern usually involves a horse having two or more white feet or legs. The white color will often extend up the legs of the horse to the belly in irregular or fragmented patches. These jagged white patches are commonly referred to as barrel spots or belly spots. The head of a Sabino horse is moderately white and commonly has a blaze or white patch that expands the length of the face. The white areas of a Sabino horse lack pigment, both in the hair and skin. 

 

Whereas other white genes cause more defined and uniform patterns which are easily recognisable, Sabino is a term often put to use for more minimal white areas of a horse which can occur in a wider variety of areas. One common defining feature of Sabino markings tends to be the 'roaning' around the edges of the white markings. This is where the 'border' of the white markings intermix with the horse's base color, and where white hairs start to blend with the darker surrounding coat. This is separate to the roaning gene, which has a similar effect and is often associated with Sabino.

Similarly to frame Overo, Sabino seems to work in a dosage effect. Horses which carry a single inherited copy of the gene will display the broken Sabino markings and possibly only a small amount of white. A horse that carries two inherited copies of the Sabino gene (homozygous) will be almost pure white in appearance. Unlike frame Overo, there is no life-threatening condition attached to the pattern.

 

The sabino-1 test is proven to determine a gene mutation linked to the Sabino1 coat pattern. The test determines whether a horse is negative, heterozygous or homozygous, for the Sabino 1 mutation.

Test Results:

Animal Genetics offers DNA testing for the mutation linked to Sabino1. The genetic test verifies the presence of the Sabino1 mutation and presents results as one of the following:

Sb1/Sb1 Homozygous Maximal Sabino. Horse inherited two copies of the dominant Sabino1 mutation and will always pass 1 copy of Sabino to foals. Homozygous Sabino horses are almost pure white in appearance.
n/Sb1 Heterozygous Positive for one copy of the Sabino1 gene mutation, carrier of a single inherited copy of Sabino. White coat pattern present. Horse's base color may be modified to varying degrees by the Sabino markings.
n/n Negative Horse can be considered a non-Sabino1 horse.

    Submit a Sample for Testing:

    To submit a sample for testing please click on ORDER and download a sample submission form. Then follow the sample collection and submission instructions.

     

    Cost per sample is $25.00. Please see our fee schedules below for combination rates.

    Equine Fee Schedule