Neonatal Ataxia (BNAt)
Neonatal Ataxia, or Bandera's Syndrome, is a genetic mutation that affects the nervous system of Coton de Tulear dogs. The mutation damages the cerebellum, the part of the brain that controls coordination and movement.
An affected Coton will tend to fall on its side when attempting to stand and will not be able to walk. The dog will only be able to move in sideways or "swimming" motions. Symptoms can be detected fairly quickly once a pup is old enough to begin moving around. There is no treatment or cure, and affected dogs will never be able to walk.
Neonatal Ataxia is an autosomal recessive trait; both parents would need to be carriers of the genetic mutation to produce an affected pup. Carriers will not exhibit any symptoms but will pass on the defective gene to offspring, so it is important to test a dog's DNA for BNAt before breeding.
Animal Genetics accepts buccal swab, blood, and dewclaw samples for testing. Sample collection kits are available and can be ordered at test now.
Test Is Relevant to the Following Breeds:
Coton de Tulear
Animal Genetics offers DNA testing for Neonatal Ataxia. The genetic test verifies the presence of the recessive BNAt gene mutation and presents results as one of the following:
|NA/NA||Affected||The dog carries two copies of the mutant gene and is homozygous for BNAt. This dog will be affected and will always pass a copy of the mutated gene to its offspring.|
|NA/n||Carrier||Both the normal and mutant copies of the gene detected. Dog is a carrier for the BNAt mutation and can pass on a copy of the defective gene to its offspring.|
|n/n||Clear||Dog tested negative for the gene mutation that causes BNAt and will not pass on the defective gene to its offspring.|