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Canine
DNA Profiling
DNA
Profiling, also known as "DNA Fingerprinting" or "Genotyping"
establishes a genetic code for individual dogs of every breed. This
test does not determine breed type, rather, it identifies specific
gene markers that are inherited from both parents.
Animal Genetics currently offers the ISAG (International
Society for Animal Genetics) standard panel, which consists of 18
STR markers. This panel identifies highly polymorphic markers to
determine the most informative genetic code for any dog. The DNA
profile of a dog consists of two alleles for each marker, one that
was inherited from the mother, and one that was inherited from the
father.
Canine DNA profiling is a useful tool to accurately
identify your dog, particularly in case a dog is stolen, or to prove
parentage.
Parentage
Analysis
DNA Profiling is an efficient and extremely
accurate way of proving parentage as well. In cases where the sire
of a litter is uncertain, the DNA profiles of the mother, father,
and offspring can be compared. Any alleles that are present in the
offspring that did not come from either parent can exclude the parent/offspring
relationship.
Parentage Analysis can also be used to prove
parentage for the purpose of clearing the puppies from genetic diseases.
If both parents test negative, or "clear" for any genetic
disorder, and the DNA profiles from the parents and the offspring
match, it can be said that the offspring is "clear by parentage."
Because both parents do not possess the mutation, and parentage
has been verified, there is no way the puppies could inherit that
mutation.
"Clear
by Parentage"
If a parent/offspring relationship is established,
and both parents test negative for a genetic disease at our lab,
the report for the offspring will indicate that the offspring is
"clear" for a mutation. All "Clear by Parentage"
results require a Parentage Verification, to be performed at
our lab. This is done to ensure the accuracy of the results, and
to prevent against any possible fraud or irresponsible breeding
practices.
Animal Genetics will verify parentage for
any parent/offspring, however, we will not indicated that a dog
is "cleared by parentage" on the certificate of the offspring.
A report will still be issued displaying the relationship between
the parents and the offspring.
Cost
Single DNA Profile:
$35.00 US per sample.
Parentage Verification: $100.00 US
Parenage Verifcation includes the DNA Profiles of the potential
father, the mother, and one offspring.
Parentage Verification of any additional puppies in the same litter:
$30.00 US per sample.
Sample Collection
Collect sample using buccal swabs provided by
Animal Genetics. Ensure that the dog has not eaten within a few
hours of sample collection. Any food particles can inhibit the test.
Rub each of the swabs along the inside of the dog's mouth for 10-15
seconds, and allow the swabs to dry thoroughly. Label the provided
envelope with the dog's name, and place the swab inside it. Download
and complete a submission form for each sample and send along with
payment to Animal Genetics for testing.
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